Intraepithelial carcinoma (Bowen disease) - Karsinoma Intraepithelial (Penyakit Bowen)
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Kasus khas — Karsinoma Intraepithelial (Penyakit Bowen) (Intraepithelial carcinoma (Bowen disease)) bisa uga salah didiagnosis minangka eksim sing tahan suwe lan ora gatal.
relevance score : -100.0%
ReferencesBowen's disease (BD) yaiku jinis kanker kulit sing diwiwiti ing lapisan njaba kulit (epidermis). Iku luwih umum ing Kaukasia lan asring ana ing wilayah sing kena sinar srengenge, nanging uga bisa katon ing papan liya. BD biasane muncul minangka lesi tunggal lan asring dadi tandha peringatan sadurunge jinis kanker kulit sing luwih serius berkembang. Kanggo diagnosa BD, dokter biasane ngandelake pemeriksaan sampel jaringan ing mikroskop (biopsi).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease umume mengaruhi wong kulit putih sing umuré luwih saka 60 taun. Faktor risiko utama kalebu paparan cahya srengenge jangka panjang, sistem kekebalan sing lemah, paparan arsenik, lan infeksi HPV ing kulit. Galur HPV 16, 18, 34, lan 48 digandhengake karo penyakit Bowen ing wilayah kelamin. Keterlibatan HPV ing kasus non‑genital kurang jelas.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Biasane katon minangka area erythematous, bersisik, utawa berkerak ing endi wae ing awak. Lokasi paling umum yaiku ing sikil ngisor.
Bisa diobati nganggo macem‑macem pilihan perawatan, kayata cryotherapy, curettage, cautery, terapi fotodinamik, utawa eksisi lesi.
○ Diagnosis lan Perawatan
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy